AppJS, one of the oldest frameworks in this space, now deprecated in favor of deskshell, which, unfortunately, seems also to have lost momentum. Personally, I liked the approach of this one, as it routed content in a way very similar to web MVC frameworks, making porting web apps from node.js much more transparent. However, unless development picks up again, it's probably not a good choice for new projects.
NW.js, formerly node-webkit, is one of the most popular and mature options today. It offers the best assortment of features, great community support, and easily searchable online questions. As it's been the go-to option for this type of application, it already has an impressive list of mature applications, Intel XDK cross-platform mobile IDE, and even several video games.